Our Technology

About Our Technology

Stem Cells are the cornerstone of contemporary regenerative medicine applications. Our breakthrough technology is backed by published scientific and clinical research completed over the last 10 years, showing significant improvement in patients’ arthritic conditions and a significant improvement in patients’ quality of life. 

Autologous Therapy

Our advanced Chondrostem™ is based on the patient’s bone marrow stem cells. Using the patient’s own stem cells, Chondrostem™ (our autologous platform) has shown to be a breakthrough treatment against Osteoarthritis and Degenerative Disc Disease. 

Allogeneic Therapy

Utilizing our proprietary technology, we bring live, resilient stem cells directly to the bedside through our Allogenic Therapy. This innovative approach not only addresses the manufacturing challenge but also facilitates targeted tissue regeneration, offering a transformative solution to medical needs.

Papers

  • Bikorimana JP, Saad W, Abusarah J, et al. CD146 Defines a Mesenchymal Stromal Cell Subpopulation with Enhanced Suppressive Properties. Cells. 2022;11(15):2263. Published 2022 Jul 22. doi:10.3390/cells11152263

  • El-Kadiry AE, Lumbao C, Salame N, Rafei M, Shammaa R. Bone marrow aspirate concentrate versus platelet-rich plasma for treating knee osteoarthritis: a one-year non-randomized retrospective comparative study. BMC Musculoskelet Disord. 2022;23(1):23. Published 2022 Jan 3. doi:10.1186/s12891-021-04910-5

  • Abusarah J, Khodayarian F, El-Hachem N, et al. Engineering immunoproteasome-expressing mesenchymal stromal cells: A potent cellular vaccine for lymphoma and melanoma in mice. Cell Rep Med. 2021;2(12):100455. Published 2021 Dec 21. doi:10.1016/j.xcrm.2021.100455

  • Bikorimana JP, El-Hachem N, El-Kadiry AE, et al. Thymoproteasome-Expressing Mesenchymal Stromal Cells Confer Protective Anti-Tumor Immunity via Cross-Priming of Endogenous Dendritic Cells. Front Immunol. 2021;11:596303. Published 2021 Jan 19. doi:10.3389/fimmu.2020.596303

  • El-Kadiry AE, Lumbao C, Rafei M, Shammaa R. Autologous BMAC Therapy Improves Spinal Degenerative Joint Disease in Lower Back Pain Patients. Front Med (Lausanne). 2021;8:622573. Published 2021 Mar 18. doi:10.3389/fmed.2021.622573

  • Kouroupis D, Ahari AF, Correa D, Shammaa R. Intralesional Injection of Bone Marrow Aspirate Concentrate for the Treatment of Osteonecrosis of the Knee Secondary to Systemic Lupus Erythematosus: A Case Report. Front Bioeng Biotechnol. 2020;8:202. Published 2020 Mar 20. doi:10.3389/fbioe.2020.00202